Job Description

Hamlyn Williams is partnered with a venture backed, Stealth mode biotech looking for a Molecular Engineering Scientist, on-site in Los Angeles, California.

This role can be Sr. Research Associate, Associate Scientist, or Scientist I level, depending on experience.

Location: Thousand Oaks, CA Position Type: Full-Time Start Date: Immediate

Salary: $95,000-$110,000

The successful candidate will join a diverse team of Molecular Engineers and work cross-functionally with the goal of evaluating preclinical candidates. Successful applicants will bring experience in bioconjugation, biologic purification strategies, and analytical method development to join a research and development team that innovates rapidly to expand the company's platform.

Key Responsibilities

• Execute bioconjugation reactions, participating in both proof-of-concept first-tests as well as reaction optimization.
• Perform biologic purification, spanning a range of therapeutic modalities and scales.
• Develop analytical methods with the aim of characterizing products as well as understanding key properties (e.g. stability, solubility).
• Keep high-quality data records and provide clear communication of results.
• Maintain personal and shared inventories of materials generated and materials characteristics.
• Collaborate cross-functionally with chemistry, biology, in vivo, and CMC teams to ensure timely delivery of materials and/or data for decision-making.

Basic Qualifications

• M.S. or Ph.D. in a Sciences related discipline.
• 1–5 years of experience, preferably in an industry setting, in bioconjugation, biologics purification, and analytical method development
• Hands-on experience with bioconjugation.
• Hands-on experience with HPLC method development.
• Proven ability to manage multiple priorities under time-sensitive timelines.

Preferred Qualifications

• Experience with multiple conjugation chemistries for small molecules, antibodies, peptides, and oligonucleotides.
• Experience with protein engineering or organic synthesis
• Proficiency in Agilent OpenLab software.
• Familiarity with tech transfer readiness for early-stage CMC.
• General knowledge of various techniques used in the characterization and evaluation of biopharmaceuticals, including mass spectrometry, surface plasmon resonance, cell-based assays, and PK/PD readouts.
• Comfortable navigating a startup environment with evolving infrastructure and high ownership expectations.

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